流感疫苗是C传统技术不是mRNA，理论上讲mRNA的长期说得通
是不多是永久改变免疫结构，就不知道
是的，nature的文章做了对比～
mRNA疫苗激发的B细胞反应比流感疫苗要强，感觉打mRNA有可能不需要每年补一针～
“Notably, S-binding GC B cells and PBs persisted for at
least 15 weeks after the first immunization (12 weeks after secondary immunization) in 8 of the 10 participants sampled at that time point. These responses to mRNA vaccination are superior to those seen after seasonal influenza virus vaccination in humans19, where hemagglutinin-binding GC B cells were detected in only three of eight participants."
“Notably, S-binding GC B cells and PBs persisted for at
least 15 weeks after the first immunization (12 weeks after secondary immunization) in 8 of the 10 participants sampled at that time point. These responses to mRNA vaccination are superior to those seen after seasonal influenza virus vaccination in humans19, where hemagglutinin-binding GC B cells were detected in only three of eight participants."
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