ACUTE TOXICITY
LD50
Oral
Rat
5000 mg/kg
LC50
Inhalation
Rat
4,550 ppm
4H
Remarks: Lungs, Thorax, or Respiration:Chronic pulmonary edema.
Liver:Other changes. Blood:Changes in cell count (unspecified).
LD50
Intraperitoneal
Rat
3810 MG/KG
Remarks: Blood:Changes in cell count (unspecified). Liver:Other
changes. Lungs, Thorax, or Respiration:Chronic pulmonary edema.
LD50
Intraperitoneal
Mouse
2450 UL/KG
SIGNS AND SYMPTOMS OF EXPOSURE
Exposure can cause: Narcotic effect. Lung irritation, chest
pain, and edema which may be fatal. CNS depression.
Gastrointestinal disturbances. Damage to the liver. Damage to
the kidneys. Blood effects.
ROUTE OF EXPOSURE
Skin Contact: Causes skin irritation.
Skin Absorption: Harmful if absorbed through skin.
Eye Contact: Causes eye irritation.
Inhalation: Material is irritating to mucous membranes and upper
respiratory tract. Harmful if inhaled
TARGET ORGAN INFORMATION
Nerves. Liver. Kidneys.
IARC CARCINOGEN LIST
Rating: Group 3
CHRONIC EXPOSURE - TERATOGEN
Species: Rat
Dose: 3000 MG/M3/24H
Route of Application: Inhalation
Exposure Time: (9-10D PREG)
Result: Maternal Effects: Other effects. Effects on Embryo or
Fetus: Fetotoxicity (except death, e.g., stunted fetus).
Endocrine:Estrogenic.
Species: Rat
Dose: 150 MG/M3/24H
Route of Application: Inhalation
Exposure Time: (7-14D PREG)
Result: Specific Developmental Abnormalities: Musculoskeletal
system. Effects on Embryo or Fetus: Extra embryonic structures
(e.g., placenta, umbilical cord).
Species: Mouse
Dose: 12 MG/KG
Route of Application: Oral
Exposure Time: (12-15D PREG)
Result: Specific Developmental Abnormalities: Craniofacial
(including nose and tongue).
Species: Mouse
Dose: 500 MG/M3/12H
Route of Application: Inhalation
Exposure Time: (6-15D PREG)
Result: Specific Developmental Abnormalities: Musculoskeletal
system. Effects on Embryo or Fetus: Fetotoxicity (except death,
e.g., stunted fetus).
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Result: May cause reproductive disorders.
Species: Rat
Route of Application: Inhalation
Exposure Time: (7-20D PREG)
Result: Effects on Embryo or Fetus: Fetal death. Effects on
Fertility: Abortion. Effects on Fertility: Post-implantation
mortality (e.g., dead and/or resorbed implants per total number
of implants).
12 - Ecological Information
ECOTOXICOLOGICAL EFFECTS
Test Type: EC50 Algae
Species: Selenastrum capricornutum resp.
Time: 72 h
Value: 3.2 - 4.4 mg/l
Test Type: EC50 Daphnia
Species: Daphnia magna
Time: 48 h
Value: 35.5 - 63.1 mg/l
Test Type: LC50 Fish
Species: Onchorhynchus mykiss (Rainbow trout)
Time: 96 h
Value: 2.6 mg/l
Test Type: LC50 Fish
Species: Carassius auratus (Goldfish)
Time: 24 h
Value: 18 mg/l
ADDITIONAL ECOLOGICAL INFORMATION
BOD5: 44 %
Huasing Association 1999 - 2013